products details

Home > Products >

Intermediates

Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study

All Category

Custom Peptide

Mr. Liu

anna@xuanmingchem.com

+86 15995072465

15995072465

Contact Now

Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study

Brand Name:	Xuanming
Model Number:	CAS 101469-92-5
MOQ:	1 kg
Price:	353 – 412USD
Packaging Details:	drum
Payment Terms:	T/T

Detail Information

Product Description

Detail Information

Place of Origin:

China

CAS Number:

101469-92-5

Molecular Formula:

C₉H₁₇NO₃

Molecular Weight:

187.24

Appearance:

Colorless Transparent Viscous Liquid

Optical Purity:

≥99% Ee

Storage Feature:

Sensitive To Humid Air

Supply Ability:

Product Description

(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate

Product Overview

(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a chiral five-member nitrogen heterocyclic ester compound. It holds fixed single stereoconfiguration and mild reaction activity, with steady crystal form and low impurity content. The product is widely adopted in chiral fragment construction, asymmetric synthesis and custom fine chemical research.

Technical Parameter Table (8 items)

Test Index	Standard Value
Full Chemical Name	(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate
Molecular Formula	C₉H₁₇NO₃
Molecular Weight	187.24
Appearance	Colorless transparent viscous liquid
Optical Purity	≥99% ee
Refractive Index	1.462~1.468 (25℃)
Usable Purity	98%, 99%
Storage Feature	Sensitive to humid air

Core Product Properties

1. Stable Single Chiral Configuration

The pyrrolidine ring maintains fixed S stereostructure under normal processing temperature, no racemization during common synthetic reactions to guarantee consistent optical performance.

2. Moderate Hydroxyl Activity

The terminal hydroxyl group can carry out esterification and etherification under mild conditions, serving as accessible active site for deriving complex heterocyclic molecules.

3. Good Solvent Compatibility

Mixes uniformly with common polar organic solvents; immiscible with water and alkane medium, matching general organic synthesis process systems.

4. Low Racemization Risk

Tert-butyl carbamate protecting group effectively locks ring stereoconformation, resisting structural inversion under conventional heating below 105℃.

5. Uniform Batch Character

Continuous purification process stabilizes optical purity and composition across batches, lowering deviation of lab synthesis test data.

6. Mild Thermal Stability

Complete molecular structure keeps intact below 105℃; long heating above 180℃ triggers partial deprotection decomposition.

7. Moisture Sensitivity

Contact with excessive water vapor slowly reduces optical purity, requiring airtight sealed packaging during preservation and transportation.

8. Protective Group Convenience

Tert-butoxycarbonyl group can be removed under weak acidic conditions, offering flexible routes for subsequent molecular modification.

Application Scope

Chiral building unit for five-member nitrogen heterocycle derivation
Raw material for asymmetric organic synthesis and stereochemistry laboratory exploration
Precursor for constructing multi-substituted pyrrolidine structural fragments
Custom fine chemical intermediate for chiral material preparation

Storage & Handling Guidance

Seal inside airtight containers and store under constant low temperature dry environment. Isolate from humid air, strong acid and high temperature sources. Shorten packaging opening time to reduce moisture contact.

Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study 0

Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study 1

Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study 2

API

Custom Chemicals

Fine Chemicals

Intermediates

Additives

Peptide

Custom Peptide

API

Custom Chemicals

Fine Chemicals

Intermediates

Additives

Peptide

Custom Peptide

products details

API

Custom Chemicals

Fine Chemicals

Intermediates

Additives

Peptide

Custom Peptide

Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study