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Cholic Acid Stable Solubility Bile Acid Compound Biochemical Protein Stabilization

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Cholic Acid Stable Solubility Bile Acid Compound Biochemical Protein Stabilization

Brand Name:	Xuanming
Model Number:	81-25-4
MOQ:	1kg
Price:	180-200USD
Packaging Details:	Drum
Payment Terms:	T/T

Detail Information

Product Description

Detail Information

Place of Origin:

China

Product Name:

Cholic Acid

81-25-4

Assay (HPLC):

≥98.0%

Melting Point:

197–202 °C

Loss On Drying:

≤1.0%

Heavy Metals:

≤10 Ppm

Residue On Ignition:

≤0.1%

Particle Size:

200 Mesh Pass Rate ≥95%

Supply Ability:

1000kg

Product Description

Cholic Acid Stable Solubility Bile Acid Compound Biochemical Protein Stabilization

Product Overview

Cholic Acid (CAS 81-25-4) is a primary trihydroxy bile acid compound widely used in biochemical research, bile acid signaling study, membrane protein extraction, and pharmaceutical intermediate development. It delivers mild solubilization to maintain native protein conformation and enzymatic activity, supporting consistent experimental results and scalable synthesis.

Product Properties

Chemical Name: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid
CAS Number: 81-25-4
Molecular Formula: C24H40O5
Molecular Weight: 408.58 g/mol
Appearance: White to off-white crystalline powder
Solubility: Slightly soluble in water; soluble in ethanol, methanol, glacial acetic acid
Stability: Stable under normal storage conditions; avoid strong light and high temperature
Key Function: Mild non-denaturing detergent; FXR nuclear receptor ligand; bile acid pathway regulator

Technical Parameters (8 Items)

Parameter	Specification
Assay (HPLC)	≥98.0%
Melting Point	197–202 °C
Specific Rotation	[α]D20 +34° to +40° (c=1, EtOH)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Particle Size	200 mesh pass rate ≥95%
Storage Condition	2–8 °C, dry & sealed

Applications

Biochemical Research: Used as mild detergent for membrane protein extraction and functional reconstitution.
Pharmaceutical Intermediate: Key raw material for bile acid derivative synthesis and impurity reference preparation.
Life Science Study: Applied in bile acid metabolism, FXR signaling pathway, and lipid regulation research.
Reference Standard: Used as analytical reference for quality control in bile acid related drugs and reagents.

Quality Control

Produced under strict process control with full traceability.
Tested by HPLC, melting point, loss on drying, heavy metals and other indicators.
COA, MSDS, TDS documents available for download.

Packaging & Storage

Packaging: 1g, 5g, 25g, 100g, 500g, 1kg sealed bottles; custom bulk packaging supported.
Storage: Keep in cool, dry, sealed environment; avoid direct sunlight and high temperature.
Transportation: Non-hazardous for normal transportation; comply with international chemical logistics standards.

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Cholic Acid Stable Solubility Bile Acid Compound Biochemical Protein Stabilization