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4-Fluorobenzoyl chloride 403-43-0 Reactive Intermediate Used in Pharmaceutical Synthesis

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4-Fluorobenzoyl chloride 403-43-0 Reactive Intermediate Used in Pharmaceutical Synthesis

Brand Name:	XuanMing
Model Number:	403-43-0
MOQ:	1kg
Price:	16-21USD
Packaging Details:	Drum
Payment Terms:	T/T

Detail Information

Product Description

Detail Information

Place of Origin:

China

Product Name:

4-Fluorobenzoyl Chloride

403-43-0

GC Purity:

≥98.0%

Boiling Point:

186-188℃ (760mmHg)

Relative Density (20℃):

1.330-1.345 G/mL

Refractive Index:

1.531-1.533

Melting Point:

-2~10℃

Water Solubility:

Hydrolyzed Rapidly In Water

Supply Ability:

8000kg

Product Description

4-Fluorobenzoyl chloride 403-43-0 Reactive Intermediate Used in Pharmaceutical Synthesis

Product Overview

4-Fluorobenzoyl chloride, CAS 403-43-0, is a high-activity fluorinated aromatic intermediate. It features pure composition and stable molecular structure, carrying active acyl chloride groups for efficient substitution reactions. The product serves as a core synthetic building block for fine chemical and pharmaceutical derivation.

Physical and Chemical Properties

This product is a colorless to pale yellow transparent liquid at room temperature, with slight smoking in humid air and mild pungent odor. It is insoluble in water and undergoes rapid hydrolysis with aqueous media, while being freely soluble in conventional organic solvents. It maintains stable performance in sealed dry environments, delivering high reaction efficiency in organic synthesis.

Basic Chemical Information

Chemical Name: 4-Fluorobenzoyl chloride

CAS Number: 403-43-0

Molecular Formula: C₇H₄ClFO

Molecular Weight: 158.56

Appearance: Colorless to Pale Yellow Transparent Liquid

Core Traits: High reactivity, low impurities, stable structure

Technical Specifications

Test Item	Specification
GC Purity	≥98.0%
Boiling Point	186-188℃ (760mmHg)
Relative Density (20℃)	1.330-1.345 g/mL
Refractive Index	1.531-1.533
Melting Point	-2~10℃
Water Solubility	Hydrolyzed rapidly in water
Moisture Content	≤0.1%
Shelf Life	12 Months (Sealed Dry Storage)

Applications

4-Fluorobenzoyl chloride 403-43-0 is a vital fluorinated fine chemical intermediate. It is widely applied in pharmaceutical intermediate synthesis, pesticide molecule modification and functional material preparation. Its high reactive activity ensures thorough reaction and high finished product yield.

Storage Instructions

Store in cool, dry and fully ventilated indoor environments with airtight sealing. Keep away from high temperature, humid air, strong light, oxidizing agents and alkaline substances. Avoid contact with water to prevent hydrolysis and quality degradation.

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4-Fluorobenzoyl chloride 403-43-0 Reactive Intermediate Used in Pharmaceutical Synthesis