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Mizoribine CAS 50924-49-7 Immunosuppressive Nucleoside Reagent for Immunology Research

Mizoribine CAS 50924-49-7 Immunosuppressive Nucleoside Reagent for Immunology Research

Brand Name: Xuanming
Model Number: 50924-49-7
MOQ: 1g
Price: 50USD
Packaging Details: foil bag
Payment Terms: T/T
Detail Information
Place of Origin:
Jiangsu
CAS Number:
50924-49-7
Chemical Name:
5-Hydroxy-1-β-D-ribofuranosylimidazole-4-carboxamide
Appearance:
White To Off-white Crystalline Powder
Molecular Formula:
C₉H₁₃N₃O₆
Molecular Weight:
259.22
Assay (HPLC):
98.0% Minimum
Supply Ability:
100kg
Product Description
Mizoribine CAS 50924-49-7 Immunosuppressive Nucleoside Reagent for Immunology Research
Overview

Mizoribine (CAS 50924-49-7) is a nucleoside-derived immunomodulatory compound originally isolated from fungal fermentation. This biochemical reagent exerts immunosuppressive effects via inhibiting inosine monophosphate dehydrogenase, a key enzyme in de novo purine synthesis, to suppress lymphocyte proliferation. It supports experimental studies in transplant immunology and autoimmune mechanism research. The crystalline powder maintains stable physicochemical properties under properly sealed and dark storage conditions.

Product Specifications
Item Standard
CAS Number 50924-49-7
Chemical Name 5-Hydroxy-1-β-D-ribofuranosylimidazole-4-carboxamide
Appearance White to off-white crystalline powder
Molecular Formula C₉H₁₃N₃O₆
Molecular Weight 259.22
Assay (HPLC) 98.0% minimum
Solubility Soluble in DMSO, slightly soluble in water
Storage Condition Sealed, cool dry environment away from light
Product Properties

Mizoribine appears as white to off-white crystalline powder at room temperature. It is soluble in DMSO and slightly soluble in water, with low solubility in non-polar organic solvents. As a purine synthesis antagonist, it selectively targets lymphocyte proliferation without severe cytotoxicity to other cell lines. The compound remains stable under cool and dry conditions, and degradation can be effectively slowed down with airtight and light-proof packaging.

Main Application

Primarily used as a specialized reagent for biochemical and immunological research. Widely applied in studies related to allograft rejection mechanism, autoimmune disease pathogenesis and immunosuppressive molecule development. Suitable for laboratory scale basic research and pilot process exploration.

FAQ
Q1: What packaging options are available for Mizoribine CAS 50924-49-7?
A: Standard sealed aluminum foil bag packaging is adopted for solid powder. Customized packing specifications can be arranged upon request.
Q2: Are supporting test documents available?
A: Corresponding Certificate of Analysis can be provided with formal order arrangement.
Q3: What is the shelf life under proper storage?
A: The product remains valid for 24 months when stored in sealed, cool and light-proof conditions as recommended.

Mizoribine CAS 50924-49-7 Immunosuppressive Nucleoside Reagent for Immunology Research

Mizoribine CAS 50924-49-7 Immunosuppressive Nucleoside Reagent for Immunology Research

Mizoribine CAS 50924-49-7 Immunosuppressive Nucleoside Reagent for Immunology Research