| Brand Name: | Xuanming |
| Model Number: | 50924-49-7 |
| MOQ: | 1g |
| Price: | 50USD |
| Packaging Details: | foil bag |
| Payment Terms: | T/T |
Mizoribine (CAS 50924-49-7) is a nucleoside-derived immunomodulatory compound originally isolated from fungal fermentation. This biochemical reagent exerts immunosuppressive effects via inhibiting inosine monophosphate dehydrogenase, a key enzyme in de novo purine synthesis, to suppress lymphocyte proliferation. It supports experimental studies in transplant immunology and autoimmune mechanism research. The crystalline powder maintains stable physicochemical properties under properly sealed and dark storage conditions.
| Item | Standard |
|---|---|
| CAS Number | 50924-49-7 |
| Chemical Name | 5-Hydroxy-1-β-D-ribofuranosylimidazole-4-carboxamide |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C₉H₁₃N₃O₆ |
| Molecular Weight | 259.22 |
| Assay (HPLC) | 98.0% minimum |
| Solubility | Soluble in DMSO, slightly soluble in water |
| Storage Condition | Sealed, cool dry environment away from light |
Mizoribine appears as white to off-white crystalline powder at room temperature. It is soluble in DMSO and slightly soluble in water, with low solubility in non-polar organic solvents. As a purine synthesis antagonist, it selectively targets lymphocyte proliferation without severe cytotoxicity to other cell lines. The compound remains stable under cool and dry conditions, and degradation can be effectively slowed down with airtight and light-proof packaging.
Primarily used as a specialized reagent for biochemical and immunological research. Widely applied in studies related to allograft rejection mechanism, autoimmune disease pathogenesis and immunosuppressive molecule development. Suitable for laboratory scale basic research and pilot process exploration.
![]()
![]()
![]()